Effect of progesterone on the interpretation of cervical smear

Author: 
Dr.Mahasweta Mallik, Dr.Sujata Mallick and Dr.Manish Kumar

Papanicolaou screening is the standard of care for detection of abnormal cervical cell. Cervical cells are susceptible to change as a result of hormonal exposure and this has the potential to affect cytologic interpretation. The purpose of this study was to examine the accuracy of cervical cytology finding in women using progesterone only contraception as compared to women who used no contraception. Material and methods- A total of 162 women were screened over a period of 3 years. Cytology and histology were done to find out sensitivity and specificity. Result- With no contraception user cervical smear sensitivity was 10% higher than with patient who use progesterone only contraception.

Paper No: 
029