Oral glycine reduces pain perception and improves conduction velocity in carpal tunnel syndrome

Objective: Several studies on the use of glycine consumption have demonstrated its anti-inflammatory properties, but not in persons with Carpal Tunnel Syndrome. We conducted a study with glycine consumption in CTS to prevent pain and improve Median Nerve function. Material and Methods: Nineteen patients diagnosed with bilateral CTS were selected and administrated glycine 1 g daily for 2 months. Pain level was assessed using the Wong scale and the electrophysiological study was performed to check MN function. Results: Nerve Conduction Velocity was lower than normal at baseline studies and increased to normal values per treatment month, decreasing pain perception of pain after 1 month and 2 months of treatment. Conclusions: The findings of this study suggest that consumption of glycine may reduce pain perception and improve motor nerve conduction in electrophysiological studies.